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AMBRETTOLIDE

Product Name
AMBRETTOLIDE
CAS No.
28645-51-4
Chemical Name
AMBRETTOLIDE
Synonyms
Nsc 31697;FEMA 2555;AMBRETTOLIDE;Fema no. 2555;Einecs 249-120-7;HEXADECEN-8-OLIDE;Ambrettolide 1832003;OMEGA-6-HEXADECENLACTONE;Oxacycloheptadec-10-en-2-on;1-oxacycloheptadec-10-en-2-one
CBNumber
CB7213218
Molecular Formula
C16H28O2
Formula Weight
252.39
MOL File
28645-51-4.mol
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AMBRETTOLIDE Property

Boiling point:
185-190 °C16 mm Hg(lit.)
Density 
0.956 g/mL at 25 °C(lit.)
vapor pressure 
0.003Pa at 25℃
refractive index 
n20/D 1.479(lit.)
FEMA 
4145 | ISOAMBRETTOLIDE
Flash point:
>230 °F
storage temp. 
Refrigerator
solubility 
Chloroform (Sparingly), Methanol (Sparingly)
form 
Oil
color 
Clear Colorless
Odor
at 10.00 % in dipropylene glycol. sweet musk ambrette fruity waxy fatty
Odor Type
musk
Water Solubility 
15μg/L at 25℃
JECFA Number
1991
LogP
6.7 at 23℃
EPA Substance Registry System
Oxacycloheptadec-10-en-2-one (28645-51-4)
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Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26-36
WGK Germany 
2
Toxicity
Both the acute oral LD50 value in rats and the acute dermal LD50 value in rabbits exceeded 5 g/kg(Wohl, 1974).
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W414522
Product name
Isoambrettolide
Purity
≥97%, FG
Packaging
SAMPLE-K
Price
$50
Updated
2024/03/01
Sigma-Aldrich
Product number
W414522
Product name
Isoambrettolide
Purity
≥97%, FG
Packaging
100g
Price
$70
Updated
2024/03/01
Sigma-Aldrich
Product number
W414522
Product name
Isoambrettolide
Purity
≥97%, FG
Packaging
1kg
Price
$400
Updated
2024/03/01
Sigma-Aldrich
Product number
W414522
Product name
Isoambrettolide
Purity
≥97%, FG
Packaging
100G-K
Price
$70
Updated
2023/06/20
Sigma-Aldrich
Product number
W414522
Product name
Isoambrettolide
Purity
≥97%, FG
Packaging
1KG-K
Price
$400
Updated
2023/06/20
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AMBRETTOLIDE Chemical Properties,Usage,Production

Chemical Properties

AMBRETTOLIDE is not reported as being found in nature, in contrast to (Z)-7-hexadecen-16-olide, which occurs in ambrette seed oil and which is also referred to as ambrettolide. It is a colorless to slightly yellow liquid, d204 0.949–0.957, n20D 1.477–1.482, with an intense and powerful musk odor. It is prepared by treating aleuritic acid (9,10,16-trihydroxyhexadecanoic acid) with trimethyl orthoformate to give a dioxolane derivative. Reaction with acetic anhydride yields ??-acetoxy (E)-9-hexadecenoic acid methyl ester. This is lactonized with potassium hydroxide to give the title compound .

Occurrence

Found in oil of ambrette seed[Givaudan Index, 1961).

Uses

Ambrettolide is a macrocyclic lactone that naturally occurs in ambrette seed oil. Ambrettolide is nontoxic, has a musky odour, and is commonly used as a fixative in perfume formulations.

Definition

ChEBI: Isoambrettolide is a macrolide.

Preparation

From bromohexadecenoic acid(Bedoukian, 1967).

Flammability and Explosibility

Not classified

AMBRETTOLIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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AMBRETTOLIDE Suppliers

BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14059
Advantage
65
Alfa Chemistry
Tel
+1-5166625404
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
21317
Advantage
58
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View Lastest Price from AMBRETTOLIDE manufacturers

Career Henan Chemical Co
Product
AMBRETTOLIDE 28645-51-4
Price
US $2.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
ask
Release date
2019-12-18

28645-51-4, AMBRETTOLIDERelated Search:


  • AMBRETTOLIDE
  • OMEGA-6-HEXADECENLACTONE
  • Oxacycloheptadec-10-en-2-on
  • 16-Hydroxy-9-hexadecenoic acid lactone
  • 1-Oxacycloheptadeca-10-en-2-one
  • Δ9-Isooambrettolic acid lactone
  • 9-Hexadecenoic acid, 16-hydroxy-, o-lactone
  • Einecs 249-120-7
  • Fema no. 2555
  • Nsc 31697
  • Omega-6-hexadecenlactone (natural)
  • (E)-oxacycloheptadec-10-en-2-one
  • 16-HYDROXY-7-HEXADECENOIC ACID O-LACTONE
  • HEXADECEN-8-OLIDE
  • FEMA 2555
  • AMBRETTOLIDE 99% CAS 28645-51-4
  • Ambrettolide 1832003
  • 1-oxacycloheptadec-10-en-2-one
  • 28645-51-4